Publications
MetwareBio's technical achievements have been presented and published in over 800 publications.
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Global Metabolite Profiling
Lipidomics
Bile Acid
Energy Metabolism
Amino Acid
Short-Chain Fatty Acids
Oxidized lipid
Plant Hormone
Carotenoids
Anthocyanins
Transcriptome
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Human Nutrition
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1 - 10 of 264 Publications
A two-front nutrient supply environment fuels small intestinal physiology through differential regulation of nutrient absorption and host defense
2024
Cell
Optimizing Skin Surface Metabolomics: A Comprehensive Evaluation of Sampling Methods, Extraction Solvents, and Analytical Techniques
2024
Journal of Investigative Dermatology
Comparative Metabolome and Transcriptome Analysis Revealed the Accumulative Mechanism of Rubusoside in Chinese Sweet Tea
2024
Journal of Agricultural and Food Chemistry
Sludge-derived biostimulants promote glycosylation of tricin and luteolin in the flavone and flavonol biosynthesis to enhance anti-inflammatory activities of rice
2024
Environmental Research
Metabolomics integrated with transcriptomics provides insights into the phenylpropanoids biosynthesis pathway in Lilium davidii var. unicolor and L. lancifolium Thunb.
2024
International Journal of Biological Macromolecules
Effects of different rootstocks on fruit quality and non-volatile flavor-related compounds of sweet cherry 'summit'
2024
Food Chemistry
Crystal structure and function of a phosphate starvation responsive protein phosphatase, GmHAD1-2 regulating soybean root development and flavonoid metabolism
2024
New Phytologist
Citrus Fruits Produce Direct Defense Responses against Oviposition by Bactrocera minax (Diptera: Tephritidae)
2024
Journal of Agricultural and Food Chemistry
Integrative multi-omics analysis reveals genetic and heterotic contributions to male fertility and yield in potato
2024
Nature Communications
T2T genomes of carrot and Alternaria dauci and their utility for understanding host–pathogen interactions during carrot leaf blight disease
2024
The Plant Journal
Multi-omics analyzes of Rosa gigantea illuminate tea scent biosynthesis and release mechanisms
2024
Nature Communications
Unbiased Single-Cell Sequencing of Hematopoietic and Immune Cells from Aplastic Anemia Reveals the Contributors of Hematopoiesis Failure and Dysfunctional Immune Regulation
2024
advanced science
Multi-omics analysis reveals a feedback loop amplifying immune responses in acute graft-versus-host disease due to imbalanced gut microbiota and bile acid metabolism
2024
Journal of Translational Medicine
Bifidobacterium pseudolongum-Derived Bile Acid from Dietary Carvacrol and Thymol Supplementation Attenuates Colitis via cGMP-PKG-mTORC1 Pathway
2024
Advanced Science
3D bioprinting of high-performance hydrogel with in-situ birth of stem cell spheroids
2024
Bioactive Materials
Tumor-colonized Streptococcus mutans metabolically reprograms tumor microenvironment and promotes oral squamous cell carcinoma
2024
Microbiome
The AP2 transcription factor BARE RECEPTACLE regulates floral organogenesis via auxin pathways in woodland strawberry
2024
The Plant Cell
Strigolactone-gibberellin crosstalk mediated by a distant silencer fine-tunes plant height in upland cotton
2024
Molecular Plant
Application of ATR-FTIR and FT-NIR spectroscopy coupled with chemometrics for species identification and quality prediction of boletes
2024
Food Chemistry: X
A study integrated metabolomics, network pharmacology, and machine learning to investigate differential metabolites of volatile compounds in food evaluation: A case of porcini mushrooms
2024
Food Bioscience
Effect of drying temperature on composition of edible mushrooms: Characterization and assessment via HS-GC-MS and IR spectral based volatile profiling and chemometrics
2024
Current Research in Food Science
Study on metabolic variation reveals metabolites important for flavor development and antioxidant property of Hainan Dayezhong black tea
2024
Food Research International
Metabolite and Transcriptomic Changes Reveal the Cold Stratification Process in Sinopodophyllum hexandrum Seeds
2024
plants
Abscisic Acid Regulates the Occurrence and Recovery of the Striped Leaf Phenotype in Response to Lacking Light at the Base of Sheath in Rice by Modulating Carbohydrate Metabolism
2024
plants
Host–microbe interaction-mediated resistance to DSS-induced inflammatory enteritis in sheep
2024
Microbiome
Empagliflozin protects against heart failure with preserved ejection fraction partly by inhibiting the senescence-associated STAT1–STING axis
2024
Cardiovascular Diabetology
Multi-omics analyses reveal mechanism for high resistant starch formation in an indica rice SSIIIa mutant
2024
Carbohydrate Polymers
Unmasking Spatial Heterogeneity in Phytotoxicology Mechanisms Induced by Carbamazepine by Mass Spectrometry Imaging and Multiomics Analyses
2024
Environmental Science & Technology
Polysaccharides from bile Arisaema exert an antipyretic effect on yeast-induced fever rats through regulating gut microbiota and metabolic profiling
2024
International Journal of Biological Macromolecules
Dopaminylation of endothelial TPI1 suppresses ferroptotic angiocrine signals to promote lung regeneration over fibrosis
2024
Cell Metabolism
Purines enrich root-associated Pseudomonas and improve wild soybean growth under salt stress
2024
Nature Communications
Transcriptomic and metabolomic analyses reveal molecular and metabolic regulation of anthocyanin biosynthesis in three varieties of currant
2024
Food Research International
Cadmium exposure promotes inflammation through the PPAR signaling pathway in the small intestine and colon of Hu sheep
2024
Ecotoxicology and Environmental Safety
External browning mechanism in walnut kernel pellicles under different drying conditions based on the combination of widely-targeted and anthocyanin-targeted metabolomics
2024
Food Chemistry
Phenoxyacetic acid enhances nodulation symbiosis during rapid growth stage of soybean
2024
Proc Natl Acad Sci U S A
Multi-omics analysis reveals improvement of tomato quality by grafting on goji rootstock
2024
Food Quality and Safety
Characteristic of epicotyl dormancy and its hormonal regulation in Chinese cork oak (Quercus variabilis)
2024
Plant Physiology and Biochemistry
A jasmonate-mediated regulatory network modulates diurnalfloret opening time in rice
2024
New Phytologist
The plant terpenes DMNT and TMTT function as signaling compounds that attract Asian corn borer (Ostrinia furnacalis) to maize plants
2024
Journal of Integrative Plant Biology
Ketogenic diet reshapes cancer metabolism through lysine beta-hydroxybutyrylation
2024
Nature Metabolism
Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin a2b1
2024
Cell Metabolism
Revealing Changes in Ovarian and Hemolymphatic Metabolites Using Widely Targeted Metabolomics between Newly Emerged and Laying Queens of Honeybee (Apis mellifera)
2024
Insects
Gut microbiota metabolite tyramine ameliorates high-fat diet-induced insulin resistance via increased Ca2+ signaling
2024
The EMBO Journal
N6‑methyladenosine‑modified SRPK1 promotes aerobic glycolysis of lung adenocarcinoma via PKM splicing
2024
Cellular & Molecular Biology Letters
Multi-omics reveals deoxycholic acid modulatesbile acid metabolism via the gut microbiota toantagonize carbon tetrachloride-induced chronicliver injury
2024
Gut Microbes
Protective role of native root-associated bacterial consortium against root-knot nematode infection in susceptible plants
2024
Nature Communications
Gut Microbiota-Derived 3-Hydroxybutyrate Blocks
GPR43-Mediated IL6 Signaling to Ameliorate Radiation
Proctopathy
2024
advanced science
Production of sodium alginate-gelatin composite hydrogel-based 3D cultured fat with low cholesterol and high polyunsaturated fatty acids
2024
Food Hydrocolloids
RNA Methyltransferase FTSJ3 Regulates the Type IInterferon Pathway to Promote Hepatocellular Carcinoma Immune Evasion
2024
CANCER RESEARCH
First-line sintilimab with pegaspargase, gemcitabine, and oxaliplatin in advanced extranodal natural killer/T cell lymphoma (SPIRIT): a multicentre, single-arm, phase 2 trial
2024
Lancet Haematol.
Ketogenic diet reshapes cancer metabolism through lysine β-hydroxybutyrylation
2024
nature metabolism
Distinct roles of TREM2 in central nervous system cancers and peripheral cancers
2024
Cancer Cell
Employing Piezoelectric Mg2+-Doped Hydroxyapatite to Target Death Receptor-Mediated Necroptosis: A Strategy for Amplifying Immune Activation
2024
Advanced Science
Association of metabolomics with PD-1 inhibitor plus chemotherapy outcomes in patients with advanced non-small cell lung cancer
2024
Journal for Immuno Therapy of Cancer
Microplastics are detected in human gallstones and have the ability to form large cholesterol-microplastic heteroaggregates
2024
Journal of Hazardous Materials
Enhanced interactions among gut mycobiomes with the deterioration of glycemic control
2024
cell med
Methylparaben induces hepatic glycolipid metabolism disorder by activating the IRE1α-XBP1 signaling pathway in male mice
2024
Environment International
An integrated multi-omics approach reveals polymethoxylated flavonoid biosynthesis in Citrus reticulata cv. Chachiensis
2024
Nature Communications
SlBEL11 regulates flavonoid biosynthesis, thus fine‐tuning auxin efflux to prevent premature fruit drop in tomato
2024
Journal of Integrative Plant Biology
Genomic basis of the distinct biosynthesis of β-glucogallin, a biochemical marker for hydrolysable tannin production, in three oak species
2024
New Phytologist
Fusaric acid mediates the assembly of disease-suppressive rhizosphere microbiota via induced shifts in plant root exudates
2024
Nature Communications
Copine proteins are required for brassinosteroid signaling in maize and Arabidopsis
2024
nature communications
Transcription factor FveMYB117a inhibits axillary bud outgrowth by regulating cytokinin homeostasis in woodland strawberry
2024
the plant cell
Multi-omics provide insights into the regulation of DNA methylation in pear fruit metabolism
2024
Genome Biology
Autophagy-mediated degradation of integumentary tapetum is critical for embryo pattern formation
2024
nature communications
Loss-of-function of LIGULELESS1 activates the jasmonate pathway and promotes maize resistance to corn leaf aphids
2024
Plant Biotechnology Journal
UDP-glucosyltransferase 71C4 controls the flux of phenylpropanoid metabolism to shape cotton seed development
2024
Plant Communications
Microbial community roles and chemical mechanisms in the parasitic development of Orobanche cumana
2024
iMeta
A peroxisomal cinnamate:CoA ligase-dependent phytohormone metabolic cascade in submerged rice germination
2024
Developmental Cell
Novel strategy to understand the aerobic deterioration of corn silage and the influence of Neolamarckia cadamba essential oil by multi-omics analysis
2024
Chemical Engineering Journal
Uptake and effect of carboxyl-modified polystyrene microplastics on cotton plants
2024
Journal of Hazardous Materials
An ARF gene mutation creates flint kernel architecture in dent maize
2024
nature communications
D-mannose alleviates intervertebral disc degeneration through glutamine metabolism
2024
Military Medical Research
FBXL4 protects against HFpEF through Drp1-Mediated regulation of mitochondrial dynamics and the downstream SERCA2a
2024
Redox Biology
A Vacancy-Engineering Ferroelectric Nanomedicine for Cuproptosis/Apoptosis Co-Activated Immunotherapy
2024
Adv Mater
ZBP1-mediated apoptosis and inflammation exacerbate steatotic liver ischemia-reperfusion injury
2024
JCI
Alistipes indistinctus-derived hippuric acid promotes intestinal urate excretion to alleviate hyperuricemia
2024
Cell Host &Microbe
Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1
2024
Cell Metabolism
Landscape of the gut mycobiome dynamics during pregnancy and its relationship with host metabolism
and pregnancy health
2024
Gut
Sexually Dimorphic Response to Hepatic Injury in Newborn Suffering from Intrauterine Growth Restriction
2024
Advanced Science
Epigenetic programming mediates abnormal gut microbiota and disease susceptibility in offspring with prenatal dexamethasone exposure
2024
cell reports Medicine
Acetate enables metabolic fitness and cognitive performance during sleep disruption
2024
Cell Metabolism
Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1
2023
Nature Communications
5mC modification orchestrates choriogenesis and fertilization by preventing prolonged ftz-f1 expression
2023
Nature Communications
Metabolome-Based Genome-Wide Association Study of Duck Meat Leads to Novel Genetic and Biochemical Insights
2023
Advanced Science
"Block and attack" strategy for tumor therapy through ZnO2/siRNA/NIR-mediating Zn2+-overload and amplified oxidative stress
2023
Aggregate
Impairing Tumor Metabolic Plasticity via a Stable Metal-Phenolic-Based Polymeric Nanomedicine to Suppress Colorectal Cancer
2023
advanced science news
ENO2-derived phosphoenolpyruvate functions as an endogenous inhibitor of HDAC1 and confers resistance to antiangiogenic therapy
2023
nature metabolism
Male-Biased Gut Microbiome and Metabolites Aggravate Colorectal Cancer Development
2023
advanced science
Black rice diet alleviates colorectal cancer development through modulating tryptophan metabolism and activating AHR pathway
2023
iMeta
Targeting UBE2T potentiates gemcitabine efficacy in pancreatic cancer by regulating pyrimidine metabolism and replication stress
2023
Gastroenterology
Metabolic classification suggests the GLUT1/ALDOB/G6PD axis as a therapeutic target in chemotherapy-resistant pancreatic cancer
2023
Cell Reports Medicine
Cancer-cell-secreted miR-2none4-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia
2023
Nature Communications
A "One Arrow Three Eagle" Strategy to Improve CM-272 Primed Bladder Cancer Immunotherapy
2023
Advanced Materials
A "One Arrow Three Eagle" Strategy to Improve CM-272 Primed Bladder Cancer Immunotherapy
2023
ADVANCED MATERIALS
Gut microbial metabolite butyrate improves anticancer therapy by regulating intracellular calcium homeostasis
2023
Hepatology
MFSD2A potentiates gastric cancer response to anti-PD-1 immunotherapy by reprogramming the tumor microenvironment to activate T cell response
2023
Cancer Communications
Runt-related transcription factor-1 ameliorates bile acid–
induced hepatic inflammation in cholestasis through JAK/
STAT3 signaling
2023
Hepatology
Plasma-Activated Solutions Mitigates DSS-Induced Colitis
via Restoring Redox Homeostasis and Reversing Microbiota Dysbiosis
2023
Advanced Science
Long-Chain Acylcarnitines Induce Senescence of Invariant Natural Killer T Cells in Hepatocellular Carcinoma
2023
cancer research
A CCL2(+)DPP4(+) subset of mesenchymal stem cells expedites aberrant formation of creeping fat in humans
2023
Nature Communications
Engineered Selenium/Human Serum Albumin Nanoparticles for Efficient Targeted Treatment of Parkinson's Disease via Oral Gavage
2023
ACS Nano
SCGN defificiency is a risk factor for autism spectrum disorder
2023
Signal Transduction and Targeted Therapy
Metabolic GWAS-based dissection of genetic basis underlying nutrient quality variation and domestication of cassava storage root
2023
Genome Biology
Metabolite-based genome-wide association studies enable the dissection of the genetic bases of flavonoids,
betaine and spermidine in wolfberry (Lycium)
2023
Plant Biotechnology Journal
Xanthophyll esterases in association with fibrillins control the stable storage of carotenoids in yellow flowers of rapeseed (Brassica juncea)
2023
New Phytologist
The haplotype-resolved genome assembly of autotetraploid rhubarb Rheum officinale provides insights into the genome evolution and massive accumulation of anthraquinones
2023
Plant Communications
Multi-omics analysis reveals the evolutionary origin of diterpenoid alkaloid biosynthesis pathways in Aconitum
2023
Journal of Integrative Biology
UV-B irradiation-activated E3 ligase GmILPA1 modulates gibberellin catabolism to increase plant height in soybean
2023
nature communications
Fine‐tuning brassinosteroid biosynthesis via 3′UTR‐dependent decay of CPD mRNA modulates wood formation in PopulusFA
2023
Journal of Integrative Plant Biology
Metabolomic analysis reveals astaxanthin biosynthesis in heterotrophic microalga Chromochloris zofingiensis
2023
Bioresource Technology
Interspecific plant interaction via root exudates structures the disease suppressiveness of rhizosphere microbiomes
2023
Molecular Plant
Microbiota-mediated nitrogen fixation and microhabitat homeo-stasis in aerial root-mucilage
2023
Microbiome
Balanophora genomes display massively convergent evolution with other extreme holoparasites and provide novel insights into parasite–host interactions
2023
Nature Plants
Metabolic flexibility during a trophic transition reveals the phenotypic plasticity of greater duckweed (Spirodela polyrhiza 7498)
2023
New Phytologist
Poaceae-specific b-1,3;1,4-D-glucans link jasmonate signalling to OsLecRK1-mediated defence response during rice-brown planthopper interactions
2023
Plant Biotechnology Journal
Comparative and population genomics of buckwheat species reveal key determinants of flavor and fertility
2023
Molecular Plant
Multi-Omics Analyses of Two Leonurus Species Illuminate Leonurine Biosynthesis and Its Evolution
2023
Molecular Plant
Transcriptional convergence after repeated duplication of an amino acid transporter gene leads to the independent emergence of the black husk/pericarp trait in barley and rice
2023
Plant Biotechnology Journal
Chromosome-scale genome assembly and insights into the metabolome and gene regulation of leaf color transition in an important oak species, Quercus dentata
2023
New Phytologist
Integrated metabolomics and transcriptomics analysis reveals γ-aminobutyric acid enhances the ozone tolerance of wheat by accumulation of flavonoids
2023
Journal of Hazardous Materials
Super-pangenome analyses highlight genomic diversity and structural variation across wild and cultivated tomato species
2023
Nature Genetics
Trade-offs between the accumulation of cuticular wax and jasmonic acid–mediated herbivory resistance in maize
2023
Journal of Integrative Plant Biology
UDP-glucosyltransferase OsUGT75A promotes submergence tolerance during rice seed germination
2023
nature communications
UDP-glucosyltransferase OsUGT75A promotes submergence tolerance during rice seed germination
2023
nature communications
A Leucine Rich Repeat Receptor Kinase Gene Confers Quantitative Susceptibility to Maize Southern Leaf Blight
2023
New Phytologist
Amino Acid Transporter as a Potential Carrier Protein for the Root_xnonenone5f to-Shoot Translocation of Polybrominated Diphenyl Ethers in Rice
2023
Environmental Science & Technology
The 14-3-3 protein OsGF14f interacts with OsbZIP23 and enhances its activity to confer osmotic stress tolerance in rice
2023
The Plant Cell
Selenium-molybdenum interactions reduce chromium toxicity in Nicotiana tabacum L. by promoting chromium chelation on the cell wall
2023
Journal of Hazardous Materials
Benzotriazole Ultraviolet Stabilizers (BUVSs) as Potential Protein Kinase Antagonists in Rice
2023
Environmental Science & Technology
The miR156b–GmSPL2b module mediates male fertility regulation of cytoplasmic male sterility-based restorer line under high-temperature stress in soybean
2023
Plant Biotechnology Journal
Improving rice eating and cooking quality by enhancing endogenous expression of a nitrogen-dependent floral regulator
2023
Plant Biotechnology Journal
A transcription factor ZmGLK36 confers broad resistance to maize rough dwarf disease in cereal crops
2023
nature plants
The WRKY46-MYC2 module is critical for E-2-hexenal induced anti-herbivore responses by promoting the accumulation of flavonoids
2023
Plant Communications
Gene mining and genomics-assisted breeding empowered by the pangenome of tea plant Camellia sinensis
2023
nature plants
The OsBZR1-OsSPX1/2 Module Fine-tunes the Growth-Immunity Trade-off in Adaptation to Phosphate Availability in Rice
2023
Molecular Plant
Metabolomics combined with physiology and transcriptomics reveal key metabolic pathway responses in apple plants exposure to different selenium concentrations
2023
Journal of Hazardous Materials
Natural Algaecide Sphingosines Identified in Hybrid Straw Decomposition Driven by White-Rot Fungi
2023
Advanced Science
Plasma proteomic and metabolomic signatures of B-ALL patients during CAR-T cell therapy
2023
Clinical and Translational Medicine
5-aminolevulinate and CHIL3/CHI3L1 treatment amid ischemia aids liver metabolism and reduces ischemia-reperfusion injury
2023
Theranostics
Hydrogel platform with tunable stiffness based on magnetic nanoparticles cross-linked GelMA for cartilage regeneration and its intrinsic biomechanism
2023
Bioactive Materials
Gut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways
2023
Nat Commun
Inhalation of diesel exhaust particulate matter induces locomotor hyperactivity and its relationship with brain and gut metabolism
2023
Environment International
Metabolic signatures in pericardial flfluid and serum are associated with new onset atrial fifibrillation after isolated coronary artery bypass grafting
2023
Translational Research
Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis
2023
Gut microbiota
Immune Regulation of the Liver Through the PCSK9 CD36 Pathway During Heart Transplant Rejection
2023
Circulation
5mC modification orchestrates choriogenesis and fertilization by preventing prolonged ftz-f1 expression
2023
Nature Communications
Nanopore membrane chip-based isolation method for metabolomics analysis of plasma small extracellular vesicles from COVID-19 survivors
2023
Biosensors and Bioelectronics
Pinostrobin from plants and propolis against human coronavirus HCoV-OC43 by modulating host AHR/CYP1A1 pathway and lipid metabolism
2023
Antiviral Research
ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs
2022
Nature
Therapeutic targeting of the mevalonate–
geranylgeranyl diphosphate pathway with statins overcomes chemotherapy resistance in small cell lung cancer
2022
Nature Cancer
CRISPR/Cas9 Screens Reveal that Hexokinase 2 Enhances Cancer Stemness and Tumorigenicity by Activating the ACSL4-Fatty Acid β -Oxidation Pathway
2022
Advanced Science
Bacteria-Elicited Specific Thrombosis Utilizing Acid-Induced Cytolysin A Expression to Enable Potent Tumor Therapy
2022
Advanced Science
P53 deficiency affects cholesterol esterification to exacerbate hepatocarcinogenesis
2022
Hepatology
Gut Flora Disequilibrium Promotes the Initiation of Liver Cancer by Modulating
Tryptophan Metabolism and Upregulating SREBP2
2022
PNAS
RNA m6A regulates transcription via DNA
demethylation and chromatin accessibility
2022
Nature Genetics
All-In-One Biomimetic Nanoplatform Based on Hollow Polydopamine Nanoparticles for Synergistically Enhanced Radiotherapy of Colon Cancer
2022
Small
5-Aminolevulinate improves metabolic recovery and cell survival of
the liver following cold preservation
2022
Theranostics
Functional and metabolic alterations of gut microbiota in children with new-onset type 1 diabetes
2022
Nature communication
Evaluationof the influences of low dose polybrominated diphenyl ethers exposureon human early retinaldevelopment
2022
Environment International
Downregulation of a gibberellin 3β-hydroxylase enhances photosynthesis and increases seed yield in soybean
2022
New Phytologist
Alternative splicing of REGULATOR OF LEAF INCLINATION 1 modulates phosphate starvation signaling and plant growth
2022
The Plant Cell
Combined nature and human selections reshaped peach fruit metabolome
2022
Genome Biology
Deletion and tandem duplications of biosynthetic genes drive the diversity of triterpenoids inAralia elata
2022
Nature communications
The flying spider-monkey tree fern genome provides insights into fern evolution and arborescence
2022
Nature Plants
WOX11 and CRL1 act synergistically to promote crown root development by maintaining cytokinin homeostasis in rice
2022
New Phytologist
Variation in the fruit development gene POINTED TIP regulates protuberance of tomato fruit tip
2022
nature communications
OsHIPL1, a hedgehog-interacting protein-like 1 protein, increases seed vigour in rice
2022
Plant Biotechnology Journal
Temperature-sensitive male sterility in rice determined by the roles of AGO1d in reproductive phasiRNA biogenesis and function
2022
New Phytologist
Pterostilbene production of tomato transformed with resveratrol synthase and resveratrol O-methyltransferase genes
2022
Plant Science
The RALF1-FERONIA Complex Interacts with and Activates TOR Signaling in Response to Low Nutrients
2022
Molecular Plant
Multi-omics analyses of 398 foxtail millet accessions reveal genomic regions associated with domestication, metabolite traits and anti-inflammatory effects
2022
Molecular Plant
Rewiring of the Seed Metabolome during Tartary Buckwheat Domestication
2022
Plant Biotechnology Journal
Regain flood adaptation in rice through a 14-3-3 protein OsGF14h
2022
nature communications
Novel approach to enhance Bradyrhizobium diazoefciens nodulation through continuous induction of ROS by manganese ferrite nanomaterials in soybean
2022
Journal of Nanobiotechnology
Integrated physiological, transcriptomic and metabolomic analysis of the response of Trifolium pratense L. to Pb toxicity
2022
Journal of Hazardous Materials
Two newly-identified biological nitrification inhibitors in Suaeda salsa: Synthetic pathways and influencing mechanisms
2022
Chemical Engineering Journal
Kynurenic acid mediates bacteria-algae consortium in resisting environmental cadmium toxicity
2022
Journal of Hazardous Materials
S1P defects cause a new entity of cataract, alopecia, oral mucosal disorder, and psoriasis-like syndrome
2022
EMBOMolecular Medicine
ATP5O Hypo-crotonylation Caused by HDAC2 Hyper-Phosphorylation Is a Primary Detrimental Factor for Downregulated Phospholipid Metabolism under Chronic Stress
2022
Research
Biofunctionalized composite scaffold to potentiate osteoconduction,
angiogenesis, and favorable metabolic microenvironment for
osteonecrosis therapy
2022
Bioact Mater
Non-oxidative pentose phosphate pathway
controls regulatory T cell function by integrating metabolism and epigenetics
2022
Nature Metabolism
Flavonifractor plautii Protects Against Elevated Arterial Stiffness
2022
Circulation Research
Novel potential metabolic biomarker panel for early detection of severe COVID-19 using full-spectrum metabolome and whole-transcriptome analyses
2022
Signal Transduction and Targeted Therapy
Prolonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19
2022
Gastroenterology
Metabolomics analysis of the effects of temperature on the growth and development of juvenile European seabass (Dicentrarchus labrax)
2021
Science of the Total Environment
Genome‐wide association study of metabolites in patients with coronary artery disease identified novel metabolite quantitative trait loci
2021
Clinical and Translational Medicine
Gut microbiota-mediated lysophosphatidylcholine generation promotes colitis in intestinal epithelium-specific Fut2 deficiency
2021
Journal of Biomedical Science
Prolonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19
2021
Gastroenterology
Htd2 deficency-associated suppression of α-lipoic acid production provokes mitochondrial dysfunction and insulin resistance in adipocytes
2021
Redox Biology
Development of a widely-targeted volatilomics method for profiling the volatilomes in plants
2021
Molecular Plant
The Cardamine enshiensis genome reveals whole genome duplication and insight into selenium hyperaccumulation and tolerance
2021
Cell Discovery
Unraveling a Genetic Roadmap for Improved Taste in the Domesticated Apple
2021
Molecular Plant
Genetic variation in YIGE1 contributes to ear length and grain yield in maize
2021
New Phytologist
Rational design of geranylgeranyl diphosphate synthase enhances carotenoid production and improves photosynthetic efficiency in Nicotiana tabacum
2021
Science Bulletin
Myb1none-D confers PHS-3D resistance to pre-harvest sprouting by regulating NCED in ABA biosynthesis pathway of wheat
2021
New Phytologist
A molecular switch in sulfur metabolism to reduce arsenic and enrich selenium in rice grain
2021
Nature Communications
Genomic basis of high-altitude adaptation in Tibetan Prunus fruit trees
2021
Current Biology
Low ABA concentration promotes root growth and hydrotropism through relief of ABA INSENSITIVE 1-mediated inhibition of plasma membrane H+-ATPase 2
2021
Science Advances
Melatonin inhibits seed germination by crosstalk with abscisic acid, gibberellin, and auxin in Arabidopsis
2021
Journal of Pineal Research
Melatonin inhibits seed germination by crosstalk with abscisic acid, gibberellin, and auxin in Arabidopsis
2021
Journal of Pineal Research
Rice metabolic regulatory network spanning its entire life cycle
2021
Molecular Plant
Multi-omic profiling of plasma reveals molecular alterations in children with COVID-19
2021
Theranostics
Plasma metabolomic profiling of patients recovered from COVID-19 with pulmonary sequelae 3 months after discharge
2021
Clinical infectious disease
Novel therapeutic evalution biomarkers of lipid metabolism tartgets in uncomplicated pulmonary tyberculosis patients
2021
Signal Transduction and Targeted Therapy
SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism
2021
Signal Transduction and Targeted Therapy
The IKKβ-USP3none-ACLY Axis Controls Lipogenesis and Tumorigenesis
2020
Hepatology
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy
2020
Nature Communications
Mucosal‐Associated Invariant T Cell Dysregulation Correlates With Conjugated Bilirubin Level in Chronic HBV Infection
2021
Hepatology
Histone Deacetylase 3 Couples Mitochondria to Drive IL-1b-Dependent Inflammation by Configuring Fatty Acid Oxidation
2020
Molecular Cell
Elevation of JAML promotes diabetic kidney disease by modulating podocyte lipid metabolism
2020
Cell Metabolism
Selection of a subspecies-specific diterpene gene cluster implicated in rice disease resistance
2020
Nature Plants
Carotenoids modulate kernel texture in maize by influencing amyloplast envelope integrity
2020
Nature Communications
Genomes of the Banyan Tree and Pollinator Wasp Provide Insights into Fig-Wasp Coevolution
2020
Cell
UDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice
2020
Nature Communications
Indole-3-acetate beta-glucosyltransferase OsIAGLU regulates seed vigor through mediating crosstalk between auxin and abscisic acid in rice
2020
Plant Biotechnology Journal
MicroTom Metabolic Network: Rewiring Tomato Metabolic Regulatory Network throughout the Growth Cycle
2020
Molecular Plant
Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis
2020
Circulation Research
Omics study abnormal alterations of breastmilk proteins and metabolites in puerperant women with COVID-19
2020
Signal Transduction and Targeted Therapy
Plasma Metabolomic and Lipidomic Alterations Assocaitaed with COVID-19
2020
National Science Review
Ethylene mediates the branching of the jasmonate-induced flavonoid biosynthesis pathway by suppressing anthocyanin biosynthesis in red Chinese pear fruits
2019
Plant Biotechnology Journal
Trichome regulator SlMX1 directly manipulates primary metabolism in tomato fruit
2019
Plant Biotechnology Journal
Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma.
2018
Nature Genetics
Subfunctionalization of the Ruby2-Ruby1 gene cluster during the domestication of citrus
2018
nature plant
Predicting the efficacy of glucocorticoids in pediatric primary immune thrombocytopenia using plasma proteomics
2023
Frontiers in Immunology
Gut microbiome and serum short-chain fatty acids are associated with responses to chemo- or targeted therapies in Chinese patients with lung cancer
2023
Frontiers in Microbiology
Lead exposure induced lipid metabolism disorders by regulating the lipophagy process in microglia
2023
Environmental Science and Pollution Research
Lipogenesis promotes mitochondrial fusion and maintains cancer stemness in human NSCLC
2023
JCI Insight
Transcriptome and metabolome comprehensive analysis reveal the molecular basis of slow-action and non-repellency of cycloxaprid against an eusocial pest, Solenopsis invicta
2023
Frontiers in Physiology
Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1
2023
Nature Communications
Comprehensive Analysis of Quantitative Proteomics With DIA Mass Spectrometry and ceRNA Network in Intrahepatic Cholestasis of Pregnancy
2022
Frontiers in Cell and Developmental Biology
Htd2 deficiency-associated suppression of α-lipoic acid production provokes mitochondrial dysfunction and insulin resistance in adipocytes
2021
Redox Biology
Novel therapeutic evaluation biomarkers of lipid metabolism targets in uncomplicated pulmonary tuberculosis patients
2021
Signal Transduction and Targeted Therapy
Swainsonine Induces Liver Inflammation in Mice via Disturbance of Gut Microbiota and Bile Acid Metabolism
2023
Journal of Agricultural and Food Chemistry
Alterations in gut microbiota are related to metabolite profiles in spinal cord injury
2023
NEURAL REGENERATION RESEARCH
Integration of metabolomics and transcriptomics analyses investigates the accumulation of secondary metabolites in maturing seed plumule of sacred lotus (Nelumbo nucifera)
2023
Food Research International
Phellodendronoside A Exerts Anticancer Effects Depending on Inducing Apoptosis Through ROS/ Nrf2/Notch Pathway and Modulating Metabolite Profiles in Hepatocellular Carcinoma
2023
Journal of Hepatocellular Carcinoma
A comprehensive study on the relieving effect of Lilium brownii on the intestinal flora and metabolic disorder in p-chlorphenylalanine induced insomnia rats
2022
Pharmaceutical Biology
Comprehensive 16S rDNA Sequencing and LC–MS/MS‑Based Metabolomics to Investigate Intestinal Flora and Metabolic Profles of the Serum, Hypothalamus and Hippocampus in p‑Chlorophenylalanine‑Induced Insomnia Rats Treated with Lilium brownie
2021
Neurochemical Research
Metabolomic Insights into Primary and Secondary Metabolites Variation in Common and Glutinous Rice (Oryza sativa L.)
2024
Agronomy
Metabolomics Reveals Antioxidant Metabolites in Colored Rice Grains
2024
Metabolites
Metabolome and transcriptome analyses provide insight into the effect of 1-MCP and SO2 preservatives on the synthesis and regulation of phenols in 'Shine Muscat' storage grapes
2024
Food Science and Technology
Association of metabolomics with PD-1 inhibitor plus chemotherapy outcomes in patients with advanced non-small cell lung cancer
2024
Journal for ImmunoTherapy of Cancer
Time-restricted feeding ameliorates non-alcoholic fatty liver disease through modulating hepatic nicotinamide metabolism via gut microbiota remodeling
2024
Gut Microbes
BnaABF3 and BnaMYB44 regulate the transcription of zeaxanthin epoxidase genes in carotenoid and abscisic acid biosynthesis
2024
plant physiology
Synergistic impacts of antibiotics and heavy metals on Hermetia illucens: Unveiling dynamics in larval gut bacterial communities and microbial metabolites
2024
Journal of Environmental Management
Activation of the Macrophage-Associated Inflammasome Exacerbates Myocardial Fibrosis Through the 15-HETE-Mediated Pathway in Acute Myocardial Infarction
2024
Engineering
Key transcription factors regulate fruit ripening and metabolite accumulation in tomato
2024
Plant Physiology
Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism
2024
nature metabolism
UDP-glucosyltransferase 71C4 controls the flux of phenylpropanoid metabolism toshape cotton seed development
2024
Plant Communications
Integrated Multiomics and Synergistic Functional Network Revealed the Mechanism in the Tolerance of Different Ecotypes of Salvia miltiorrhiza Bge. to Doxycycline Pollution
2024
Environmental Science ＆ Technology
Landscape of the gut mycobiome dynamics during pregnancy and its relationship with host metabolism and pregnancy health
2024
Gut microbiota
ZmSIZ1a and ZmSIZ1b play an indispensable role in resistance against Fusarium ear rot in maize
2023
Molecular Plant Pathology
A comprehensive metabolic map reveals major quality regulations in red flesh kiwifruit
2023
New phytologist
ETHYLENE-INSENSITIVE 3-LIKE 2 regulates β-carotene and ascorbic acid accumulation in tomatoes during ripening
2023
Plant Physiology
Novel scheme for non-invasive gut bioinformation acquisition with a magnetically controlled sampling capsule endoscope
2021
GUT
COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors
2021
Signal Transduction and Targeted Therapy
Engineering of gold nanorods as multifunctional theranostic agent for photothermal-enhanced radiotherapy of cancer
2022
Materials & Design
Bacteria-Elicited Specific Thrombosis Utilizing Acid-Induced Cytolysin A Expression to Enable Potent Tumor Therapy
2022
Advanced Science
Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis
2021
Pharmacological Research
The IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis
2021
Hepatology
Plasma Quantitative Lipid Profiles:Identification of CarnitineC18:1-OH,CarnitineC18:2-OH and FFA (20:1) as Novel Biomarkers for Pre-warning and Prognosis in Acute Myocardial Infarction
2022
Frontiers in Cardiovascular Medicine
Individual and joint effects of trehalose and glutamate on diabetic retinopathy: a propensity score-matched case-control study
2022
Endocrine Connections
Htd2 deficency-associated suppression of α-lipoic acid production provokes mitochondrial
2021
Redox Biology
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