Metabolomics Service Platform
Triple Quadruple Pole Mass Spectrometer
QTRAP® 6500+ system(20sets)
Resolution Ratio |
≥9000 |
Mass Range |
5-2000m/z |
Scanning Speed |
20000Da/s |
Mass Accuracy |
<0.01%(Total mass number range) |
Sensitivity |
ESI Positive ions:1pg Reserpine was injected,S/N≥160000:1 ESI Negative ions:1pg Estradiol injection,S/N≥500:1 |
Dynamic Range |
>10 6 |
QTRAP® 4500 system(4 sets)
Resolution Ratio |
Unit resolution |
Mass Range |
5-2000m/z |
Scanning Speed |
12000Da/s |
Mass Accuracy |
<0.1 Da over 24 hours |
Sensitivity |
1pg reserpine,S/N≥200,000:1 |
Dynamic Range |
>10 5 |
High Resolution Mass Spectrometers
Agilent 6545 Q-TOF LC-MS
Mass Resolving Power |
45000(FWHM )at m/z 2,722 |
Mass Range |
100–10,000 m/z |
Spectral Acquisition Rate |
50 spectra/second |
Mass Accuracy |
Internal standard <0.08ppm |
Sensitivity |
ESI Positive ions: 1pg Reserpine was injected, S/N≥500:1 |
Dynamic Range |
>10 5 |
Q ExactiveHF-X
Resolution ratio |
240000@m/z 200 |
Mass Range |
50-6000m/z |
Scanning Speed |
Up to 40Hz |
Quality Accuracy |
Internal standard<1ppm RMS, External standard<3ppm RMS |
Sensitivity |
Full scanning MS: The S/N of reserpine on 100FG upper column was 150:1 SIM:50FG S/N of reserpine on the upper column was 150:1 |
Dynamic range |
>5000:1 |
Bruker TimsTof Pro
Resolution Ratio |
At a high acquisition rate≥(40Hz), resoluton≥50,000(@M/Z1222,FWHM) |
Mass Range |
20-40,000 m/z |
Scanning Speed |
MS≥40 Hz, MS/MS acquisition rate≥100 Hz |
Quality Accuracy |
Internal standard <0.8ppm RMS, External standard<2ppm RMS |
Sensitivity |
Mobility mode: MS:1pg/uL reserpine, S/N>100: 1; MS/MS:2.5Fmol Glu-fibrinopeptide B, the strongest peak signal in y ion of divalent ion fragments was greater than 800, S/N>100:1 |
Bruker TimsTof FleX
Resolution Ratio |
60,000(@M/Z1222, FSR), independent of scanning speed |
Mass Range |
20-40,000 m/z |
Scanning Speed |
MS:50 Hz, MS/MS:50Hz(Contour plots, peak detection and data storage) PASEF(ESI):120 Hz |
Quality Accuracy |
Internal standard : <0.8ppm, External standard: 2ppm |
Sensitivity |
MS:1pg/uL reserpine,S/N>100:1; MS/MS: 2.5fmol Flu-Fibrinopeptide, S/N 50:1;TIMS-MS: 50 fg/ul reserpine, < 15% RSD; |