Mass Spectrometry Instrument Series

Mass spectrometry (MS) has evolved from a physicist’s tool for measuring atomic masses into a cornerstone technology across life sciences, medicine, environmental analysis, and materials science. Over the past few decades, advances in ion optics, detector systems, and hybrid analyzers have propelled MS to the forefront of analytical instrumentation. Today, mass spectrometers are indispensable for precise molecular identification, quantification, and structural analysis. Their unparalleled sensitivity and specificity make them essential in fields such as proteomics, metabolomics, pharmacokinetics, and clinical diagnostics—driving innovation in both basic research and applied science.

This blog series offers a focused and practical overview of the most widely used mass spectrometry platforms on the market today. From triple quadrupole (QQQ) systems and hybrid quadrupole-time-of-flight (QTOF) instruments to QTRAP, Orbitrap, and MALDI-TOF, we explore the core principles, analytical capabilities, and application scenarios of each. Whether you're looking to choose the right MS system for your lab or deepen your understanding of instrument design and functionality, this collection will guide you through the landscape of modern mass spectrometry. Key topics include foundational MS concepts, instrument comparisons, platform-specific insights, and expert tips for method selection and optimization.

For in-depth insights on each topic, please explore the blogs below:

1. Mass Spectrometry: The Master Key to Life Sciences Innovation

2. Deconstructing Mass Spectrometry: A Comprehensive Guide to Instrumentation and Applications

3. Top Mass Spectrometry Instruments Compared: Features, Strengths, and Selection Tips

4. Unlocking the Power of MALDI-TOF Mass Spectrometry: Principles, Applications, and Future Innovations

5. From MALDI to QQQ: A Complete Guide to Mass Spectrometry Techniques and Their Applications