Proteomics Services: Insightful Solutions, Infinite Potential
Proteomics Services: Insightful Solutions, Infinite Potential
Proteomics offers critical insights into fundamental biological processes, disease mechanisms, and therapeutic targets. As a leading provider of proteomics services, Metware offers comprehensive solutions tailored to the diverse needs of our clients. With cutting-edge mass spectrometry technology, refined workflows, and advanced bioinformatic analysis, our proteomic services deliver in-depth proteome identification and quantitation for different types of projects, including unbiased general profiling and specific post-translational modifications, ranging from small-scale projects to large population studies. Our commitment lies in delivering professional, high-quality, and accurate services for our clients.
Technologies superiority
Large depth and breadth
Deal with various type of protein samples and detect more proteins with less sample size.
High stability and reproducibility
Obtain consistent and reproducible inter- and intra- assay results for data analysis.
High specificity and accuracy
4D identification/quantification-ion intensity, ion mobility, retention time and m/z.
High resolution and sensitivity
Use acquisition mode of TIMS+PASEF on timsTOF HT mass spectrometry.
Professional extraction and analysis
sample-specific extraction methods and diverse data analysis.
Discover Metware Proteomics Services
Metware Proteomics Service Process: From Samples to Report
1
Sample shipment
2
Protein extraction
3
Trypsin digestion
4
Data Acquisition
5
Database search
6
Data analysis
Analysis Content Display
Comprehensive and professional data analysis, including a total of 26 analyses, 39 images
PPI Network
PCA Analysis
Signal Peptide Prediction
KEGG Pathway Annotation
Subcellular Localization
Correlation Analysis
Cluster Heatmap
WPCNA Analysis
What is Proteomics Used For?
Proteomics is used to characterize and quantify the entire complement of proteins, known as the proteome, present in a biological sample at a given time. This involves identifying individual proteins, determining their abundance, understanding their interactions with other molecules, and elucidating their functions within cellular pathways and networks.
Proteomics Services FAQS
What's the difference between 4D DIA Quantitative Proteomics and 4D DDA Quantitative Proteomics?
The 4D DIA Quantitative Proteomics utilizes a data-independent acquisition (DIA) ion scanning mode for signal acquisition, whereas the 4D Lable Free Quantitative Proteomics utilizes a data-dependent acquisition (DDA) ion scanning mode for signal acquisition. The 4D DIA Quantitative Proteomics panel detects a greater number of peptides compared to the 4D Lable Free Quantitative Proteomics panel.
How does Phosphorylation Proteomics work?
Protein phosphorylation modification refers to the process where phosphate groups from ATP or GTP are transferred to specific sites (amino acid residues Ser, Tyr, Thr) on proteins, catalyzed by protein kinases. The principle of Phosphorylation Modification Proteomics involves first digesting protein samples into a mixture of peptides, followed by separation of the digested peptide mixture using liquid chromatography to reduce sample complexity. Subsequently, modification peptides are enriched using high-quality phosphorylation modification antibodies and biological materials, and finally subjected to analysis and quantification by liquid chromatography-tandem mass spectrometry.
Applications of Proteomics Services
Medical Research
Disease Mechanisms, Molecular Diagnosis, Biomarker Development, Drug Targets
Animal Research
Reproductive Development, Disease Mechanisms, Nutrient Metabolism, Animal Toxicology
Plant Research
Reproductive Development, Abiotic Stress Response, Disease Resistance, Crop Improvement
Microbiology
Pathogenic Mechanisms, Drug Resistance, Stress-Related Proteins Screening, Environmental Impact Mechanisms
